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The Coordinating Center (CC) coordinates and harmonizes the scientific and clinical needs of the Cancer Adoptive Cellular Therapeutics (Can-ACT) Network's UG3/UH3 centers. Located at the Mayo Clinic, the CC serves as the administrative hub for clinical trials and research projects, providing leadership and infrastructure support. It facilitates interactions across the network and manages collaborative funds. On the scientific front, the CC focuses on sharing reagents and specimens, harmonizing manufacturing processes, and offering support in biostatistics, bioinformatics, and data management. The team at the Mayo Clinic possesses extensive experience in coordinating clinical research across institutions, positioning them as effective leaders for the Can-ACT Network. Their leadership combines expertise in multi-institutional trials and research guidance while adapting to the network's growth and fostering collaboration among all centers and project leaders.